Dimethyl malonate (Standard)
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH) . Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis[1].
Product Specifications
CAS Number
[108-59-8]
UNSPSC
12352211
Target
Apoptosis
Related Pathways
Apoptosis
Field of Research
Neurological Disease
Smiles
O=C(OC)CC(OC)=O
Molecular Formula
C5H8O4
Molecular Weight
132.11
References & Citations
[1]Xu J, et al. Inhibiting Succinate Dehydrogenase by Dimethyl Malonate Alleviates Brain Damage in a Rat Model of Cardiac Arrest. Neuroscience. 2018 Nov 21;393:24-32.
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Scientific Category
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