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Dimethyl malonate (Standard)

Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH) . Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis[1].

Product Specifications

CAS Number

108-59-8

UNSPSC

12352211

Target

Apoptosis

Related Pathways

Apoptosis

Field of Research

Neurological Disease

Smiles

O=C(OC)CC(OC)=O

Molecular Formula

C5H8O4

Molecular Weight

132.11

References & Citations

[1]Xu J, et al. Inhibiting Succinate Dehydrogenase by Dimethyl Malonate Alleviates Brain Damage in a Rat Model of Cardiac Arrest. Neuroscience. 2018 Nov 21;393:24-32.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

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