HATU
HATU (1-[Bis (dimethylamino) methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid. HATU can be used along with Hünig's base (N, N-diisopropylethylamine, DIPEA) to form amide bonds[1].
Product Specifications
CAS Number
[148893-10-1]
UNSPSC
12352200
Hazard Statement
H317, H334
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Others
Purity
99.98
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
F[P-](F)(F)(F)(F)F.C/[N+](C)=C(N(C)C)/ON1C2=NC=CC=C2N=N1
Molecular Formula
C10H15F6N6OP
Molecular Weight
380.23
Precautions
H317, H334
References & Citations
[1]Louis A, et al. 1-Hydroxy-7-azabenzotriazole. An efficient peptide coupling additive. J. Am. Chem. Soc. 1993, 115, 10, 4397–4398
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
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