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2,6-Dibromophenol (Standard)

2,6-Dibromophenol (2,6-DBP) is a weak inhibitor targeting voltage-gated Ca2+ channels. 2,6-Dibromophenol has no significant effect on potassium-induced calcium elevation in PC12 cells. 2,6-Dibromophenol shows a 48 h EC50 of 2.78 mg/L for Daphnia magna and a 96 h EC50 of 9.90 mg/L for algae (Scenedesmus quadricauda) [1][2].

Product Specifications

CAS Number

608-33-3

UNSPSC

12352005

Target

Calcium Channel; Fungal; Parasite

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Metabolic Disease

Smiles

OC1=C(Br)C=CC=C1Br

Molecular Formula

C6H4Br2O

Molecular Weight

251.91

References & Citations

[1]Hassenklöver T, et al. Bromophenols, both present in marine organisms and in industrial flame retardants, disturb cellular Ca2+ signaling in neuroendocrine cells (PC12) . Aquat Toxicol. 2006 Jan 5;76 (1) :37-45.|[2]Li B, et al. Acute Toxicities of Bromophenols to Alga and Daphina: Comparative Species Sensitivity Distribution Between Standard and Dietary Supplementation Tests. J Toxicol. 2025 May 11;2025:3399746.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

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