Benzohydroxamic acid
Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with significant antifungal activity. The Ki values of BHA against the CDAs of Verticillium dahliae and Puccinia striiformis f. sp. tritici are 8.31 μM and 9.83 μM, respectively. Benzohydroxamic acid can restore the defense responses of infected host plants, upregulate the expression of defense-related genes, and reduce the growth and reproduction of fungi in plants. Benzohydroxamic acid can be used in the research of the field of controlling agricultural fungal diseases, such as various plant fungal diseases caused by Verticillium dahliae, Puccinia striiformis and other fungi, like cotton wilt and wheat stripe rust [1].
Product Specifications
CAS Number
[495-18-1]
Product Name Alternative
BHA
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Fungal
Related Pathways
Anti-infection
Field of Research
Infection
Purity
99.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NO)C1=CC=CC=C1
Molecular Formula
C7H7NO2
Molecular Weight
137.14
Precautions
H315, H319
References & Citations
[1]Liu L, et al. Inhibition of chitin deacetylases to attenuate plant fungal diseases. Nat Commun. 2023 Jun 29;14 (1) :3857.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound2
Clinical Information
Phase 3
Available Sizes
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