Glyoxal-d2
Glyoxal-d2 is the deuterium labeled Glyoxal (HY-Y0785) . Glyoxal is a cytotoxic α-oxoaldehyde. Glyoxal induces cell damage and promotes protein glycation to form advanced glycation end-products (AGEs) . Glyoxal is promising for research of oxidative stress-related diseases (such as atherosclerosis, cataract, Alzheimer's disease), and the formation of calcium oxalate kidney stones[1][2].
Product Specifications
CAS Number
[16355-99-0]
UNSPSC
12352211
Target
Drug Metabolite; Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=C([2H])C([2H])=O
Molecular Formula
C2D2O2
Molecular Weight
60.05
References & Citations
[1]Shangari N, O'Brien PJ. The cytotoxic mechanism of glyoxal involves oxidative stress. Biochem Pharmacol. 2004 Oct 1;68 (7) :1433-42.|[2]Lange JN, et al. Glyoxal formation and its role in endogenous oxalate synthesis. Adv Urol. 2012;2012:819202.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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