Glyoxal-d2

Glyoxal-d2 is the deuterium labeled Glyoxal (HY-Y0785) . Glyoxal is a cytotoxic α-oxoaldehyde. Glyoxal induces cell damage and promotes protein glycation to form advanced glycation end-products (AGEs) . Glyoxal is promising for research of oxidative stress-related diseases (such as atherosclerosis, cataract, Alzheimer's disease), and the formation of calcium oxalate kidney stones[1][2].

Product Specifications

CAS Number

[16355-99-0]

UNSPSC

12352211

Target

Drug Metabolite; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

O=C([2H])C([2H])=O

Molecular Formula

C2D2O2

Molecular Weight

60.05

References & Citations

[1]Shangari N, O'Brien PJ. The cytotoxic mechanism of glyoxal involves oxidative stress. Biochem Pharmacol. 2004 Oct 1;68 (7) :1433-42.|[2]Lange JN, et al. Glyoxal formation and its role in endogenous oxalate synthesis. Adv Urol. 2012;2012:819202.