6-Chlorooxindole
6-Chlorooxindole (compound 2) is a selective chymase inhibitor with an IC50 of 470 μM. 6-Chlorooxindole shows >100-fold selectivity for chymase over cathepsin G. 6-Chlorooxindole can be used for the study of cardiovascular disease[1].
Product Specifications
CAS Number
[56341-37-8]
UNSPSC
12352005
Hazard Statement
H302, H317
Target
Proteasome
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Purity
99.52
Smiles
O=C1NC2=C(C=CC(Cl)=C2)C1
Molecular Formula
C8H6ClNO
Molecular Weight
167.59
Precautions
H302, H317
References & Citations
[1]Taylor SJ, et al. Discovery of potent, selective chymase inhibitors via fragment linking strategies. J Med Chem. 2013 Jun 13;56 (11) :4465-81.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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