CRBN ligand-227
CRBN ligand-227 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-227 can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
CAS Number
[1482078-60-3]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(NC1C(=O)NC(=O)CC1)C2=CC=C(N)C=C2F
Molecular Formula
C12H12FN3O3
Molecular Weight
265.24
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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