CRBN ligand-463
CRBN ligand-463 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-463 can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
C#CC1C2=C(C=C(F)C=1)C(=NN2C)C3C(=O)NC(=O)CC3
Molecular Formula
C15H12FN3O2
Molecular Weight
285.27
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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[2R-[2α,6α,7β (R*) ]]-7-[[[[ (1,1-Dimethylethoxy) carbonyl]amino]phenylacetyl]amino]-3-methylene-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic Acid 5-Oxide
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