CRBN ligand-221
CRBN ligand-221 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-221 can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
CAS Number
[2412058-81-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1NC(=O)C(N2C(=O)CC=3C(N)=CC=CC32)CC1
Molecular Formula
C13H13N3O3
Molecular Weight
259.27
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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