Thalidomide-3,8-diazabicyclo[3.2.1]octane-Boc
Thalidomide-3,8-diazabicyclo[3.2.1]octane-Boc is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Product Specifications
CAS Number
[2740655-32-5]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(N1C2CN(CC1CC2)C3=CC=C4C(N(C5C(NC(CC5)=O)=O)C(C4=C3)=O)=O)OC(C)(C)C
Molecular Formula
C24H28N4O6
Molecular Weight
468.50
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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