Thalidomide-5-NH2-6-F

Thalidomide-5-NH2-6-F is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-5-NH2-6-F can be linked to a target protein ligand via a linker to form a PROTAC.

Product Specifications

CAS Number

[2995272-75-6]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C1NC(=O)C(N2C(=O)C3=CC(F)=C(N)C=C3C2=O)CC1

Molecular Formula

C13H10FN3O4

Molecular Weight

291.24

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Curated Selection

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