Thalidomide-piperazine-tert-butyl formate
Thalidomide-piperazine-tert-butyl formate is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Product Specifications
CAS Number
[2222120-27-4]
UNSPSC
12352005
Hazard Statement
H361-H373
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(OC(C)(C)C)N1CCN(C2=CC=C3C(=O)N(CC3=C2)C4C(=O)NC(=O)CC4)CC1
Molecular Formula
C22H28N4O5
Molecular Weight
428.49
Precautions
P260-P280-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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