Thalidomide-5-piperazine-azetidine (TFA)
Thalidomide-5-piperazine-azetidine (TFA) is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Product Specifications
CAS Number
[3065021-28-2]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1NC(C(CC1)N2C(C3=CC=C(N4CCN(C5CNC5)CC4)C=C3C2=O)=O)=O.O=C(C(F)(F)F)O
Molecular Formula
C22H24F3N5O6
Molecular Weight
511.45
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
