Thalidomide-O-amido-C3-COOH (TFA)
Thalidomide-O-amido-C3-COOH (TFA) is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Product Specifications
CAS Number
3037693-14-1
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(C(F)(F)F)O.O=C(CCCNC(COC1=CC=CC(C(N2C3CCC(NC3=O)=O)=O)=C1C2=O)=O)O
Molecular Formula
C21H20F3N3O10
Molecular Weight
531.39
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Frequently Asked Questions
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