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Thalidomide-O-amido-C3-COOH (TFA)

Thalidomide-O-amido-C3-COOH (TFA) is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

Product Specifications

CAS Number

[3037693-14-1]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(C(F)(F)F)O.O=C(CCCNC(COC1=CC=CC(C(N2C3CCC(NC3=O)=O)=O)=C1C2=O)=O)O

Molecular Formula

C21H20F3N3O10

Molecular Weight

531.39

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Curated Selection

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