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Pomalidomide 5'-piperazine-4-methylpiperidine

Pomalidomide 5'-piperazine-4-methylpiperidine is the conjugate composed of a E3 ligase ligand and a linker. Pomalidomide 5'-piperazine-4-methylpiperidine can be used for PROTAC synthesis, such as PROTAC EGFR degrader 13 (HY-158313) [1].

Product Specifications

CAS Number

[2229725-28-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C1NC(C(CC1)N2C(C3=CC=C(N4CCN(CC5CCNCC5)CC4)C=C3C2=O)=O)=O

Molecular Formula

C23H29N5O4

Molecular Weight

439.51

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Chen Zhang, et al. Phosphonyl derivative, and composition and pharmaceutical application thereof. WO2022228547A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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