Thalidomide-piperidin-O-piperidin (TFA)
Thalidomide-piperidin-O-piperidin (TFA) is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Product Specifications
CAS Number
[2839669-93-9]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1NC(C(CC1)N2C(C3=CC=C(N4CCC(CC4)OC5CCNCC5)C=C3C2=O)=O)=O.O=C(C(F)(F)F)O.O=C(C(F)(F)F)O
Molecular Formula
C27H30F6N4O9
Molecular Weight
668.54
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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