3- (2,6-Difluoro-4- (4- (2-hydroxyethyl) piperidin-1-yl) phenyl) piperidine-2,6-dione
3- (2,6-Difluoro-4- (4- (2-hydroxyethyl) piperidin-1-yl) phenyl) piperidine-2,6-dione is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Product Specifications
CAS Number
[2758532-21-5]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1NC(=O)C(C2=C(F)C=C(C=C2F)N3CCC(CCO)CC3)CC1
Molecular Formula
C18H22F2N2O3
Molecular Weight
352.38
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
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