Thalidomide-O-C2-alkyne
Thalidomide-O-C2-alkyne is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Product Specifications
CAS Number
[2357110-34-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Purity
99.67
Smiles
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCC#C)C3C2=O)CC1
Molecular Formula
C17H14N2O5
Molecular Weight
326.31
Precautions
H302, H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Curated Selection
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