Thalidomide-propargyl-NHCH3

Thalidomide-propargyl-NHCH3 is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

Product Specifications

CAS Number

[1216805-74-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C1NC(=O)C(N2C(=O)C3=CC=C(C#CCNC)C=C3C2=O)CC1

Molecular Formula

C17H15N3O4

Molecular Weight

325.32

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Curated Selection

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