LY-266500
LY-266500 is a succinyl CoA synthetase (SCS) specific inhibitor. LY-266500 has inhibitory effects on various parasites, such as Trypanosoma brucei brucei (IC50 =0.6 μM) and Leishmania donovani (IC50 =2.86 μM) . LY-266500 can be used for research on parasitic infections[1].
Product Specifications
CAS Number
147104-27-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Mitochondrial Metabolism; Parasite
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C1C=CSN1C2=CC=C(C(Cl)=C2)F
Molecular Formula
C9H5ClFNOS
Molecular Weight
229.66
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Hunger-Glaser I, et al. Inhibition of succinyl CoA synthetase histidine-phosphorylation in Trypanosoma brucei by an inhibitor of bacterial two-component systems. Mol Biochem Parasitol. 1999 May 15;100 (1) :53-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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