Pomalidomide-C2-Br

Pomalidomide-C2-Br is an E3 Ligase Ligand (HY-14658) and linker (HY-W007731) conjugate. Pomalidomide-C2-Br can be used to synthesize PROTAC AR Degrader-8 (HY-170329) [1].

Product Specifications

CAS Number

[2940940-74-7]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCBr)=CC=C3)=O)=O

Molecular Formula

C15H14BrN3O4

Molecular Weight

380.19

References & Citations

[1]Ha S, et al. Discovery of a highly potent, N-terminal domain-targeting degrader of AR-FL/AR-V7 for the treatment of prostate cancer. Eur J Med Chem. 2025 Jan 15;282:117079.