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DCAF11 ligand 1

DCAF11 ligand 1 is the ligand for E3 ligase DCAF11 and can be used for PROTAC synthesis of FF2039 (HY-172159) [1].

Product Specifications

CAS Number

[2940939-13-7]

UNSPSC

12352211

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(CCl)NC(C(NCC1=CC=CC=C1)=O)C2=CC=C(C(Cl)=C2)Cl

Molecular Formula

C17H15Cl3N2O2

Molecular Weight

385.67

References & Citations

[1]Feller F, et al., Replacing a Cereblon Ligand by a DDB1 and CUL4 Associated Factor 11 (DCAF11) Recruiter Converts a Selective Histone Deacetylase 6 PROTAC into a pan-degrader. ChemMedChem. 2025 Feb 20:e202500035.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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