CRBN ligand-451

CRBN ligand-451 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-451 can be linked to a target protein ligand via a linker to form a PROTAC.

Product Specifications

CAS Number

[2925090-99-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=CC=1C=C(C=C2N=CN=CC21)N3C(=O)NC(=O)CC3

Molecular Formula

C13H10N4O3

Molecular Weight

270.25

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Curated Selection

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