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Pomalidomide-NH-C13-OH

Pomalidomide-NH-C13-OH is a synthesized E3 ligase ligand-linker conjugate that can be used for synthesis of PROTAC PI3Kα degrader-1 (HY-174461) [1].

Product Specifications

CAS Number

[2716120-15-7]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCCCCCCCCCCCO)=CC=C3)=O)=O

Molecular Formula

C25H35N3O5

Molecular Weight

457.56

References & Citations

[1]Peng S, et al. Discovery and Optimization of Potent PROTAC Degraders of Phosphoinositide 3-Kinase with Significant in Vivo Anticancer Efficacy. J Med Chem. 2025 Jun 26;68 (12) :12800-12818.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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