Pomalidomide-NH-C13-OH
Pomalidomide-NH-C13-OH is a synthesized E3 ligase ligand-linker conjugate that can be used for synthesis of PROTAC PI3Kα degrader-1 (HY-174461) [1].
Product Specifications
CAS Number
[2716120-15-7]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCCCCCCCCCCCO)=CC=C3)=O)=O
Molecular Formula
C25H35N3O5
Molecular Weight
457.56
References & Citations
[1]Peng S, et al. Discovery and Optimization of Potent PROTAC Degraders of Phosphoinositide 3-Kinase with Significant in Vivo Anticancer Efficacy. J Med Chem. 2025 Jun 26;68 (12) :12800-12818.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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