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CRBN ligand-108

CRBN ligand-108 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.

Product Specifications

CAS Number

[3036607-80-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

N#CC1=CC(C(CC2)C(NC2=O)=O)=CC=C1Br

Molecular Formula

C12H9BrN2O2

Molecular Weight

293.12

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Miletić N, et al. Workflow for E3 Ligase Ligand Validation for PROTAC Development. ACS Chem Biol. 2025 Feb 21;20 (2) :507-521.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Curated Selection

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