CRBN ligand-181
CRBN ligand-181 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.
Product Specifications
CAS Number
3036607-12-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(C(C1=C(C)C=C(Br)C=C1F)CC2)NC2=O
Molecular Formula
C12H11BrFNO2
Molecular Weight
300.12
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Miletić N, et al. Workflow for E3 Ligase Ligand Validation for PROTAC Development. ACS Chem Biol. 2025 Feb 21;20 (2) :507-521.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
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