PMO-G
PMO-G is a spherical-shape polymeric micelles. PMO-G has skin permeation. PMO-G can result in up to a 50-fold higher level of dystrophin in abdominal muscles of mdx mice. PMO-G can be studied in research on Duchenne muscular dystrophy[1][2].
Product Specifications
CAS Number
2708274-72-8
UNSPSC
12352005
Hazard Statement
H302, H314
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Metabolic Disease
Purity
99.62
Smiles
CN(C)P(OC[C@H](C1)O[C@@H](N2C3=NC(NC(C(C)C)=O)=NC(OCCC4=CC=C(C=C4)[N+]([O-])=O)=C3N=C2)CN1C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)(Cl)=O
Molecular Formula
C43H46ClN8O7P
Molecular Weight
853.30
Precautions
H302, H314
References & Citations
[1]An, J. Y., et al., (2020) . Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy. Nanoscale research letters, 15 (1), 133.|[2]Lin, C., et al., (2020) . Glycine Enhances Satellite Cell Proliferation, Cell Transplantation, and Oligonucleotide Efficacy in Dystrophic Muscle. Molecular therapy : the journal of the American Society of Gene Therapy, 28 (5), 1339–1358.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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