(1r,4r) -tert-Butyl 4- (bromomethyl) cyclohexanecarboxylate
(1r,4r) -tert-Butyl 4- (bromomethyl) cyclohexanecarboxylate is a PROTAC linker used in the synthesis of SMD-1087 (HY-170828) [1].
Product Specifications
CAS Number
[2866254-09-1]
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
C(OC(C)(C)C)(=O)[C@H]1CC[C@H](CBr)CC1
Molecular Formula
C12H21BrO2
Molecular Weight
277.20
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Leng L, et al. Discovery of High-Affinity SMARCA2/4 Bromodomain Ligands and Development of Potent and Exceptionally Selective SMARCA2 PROTAC Degraders. J Med Chem. 2025 Jan 2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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