3- (Dimethoxymethyl) -1-oxa-8-azaspiro[4.5]decane
3- (Dimethoxymethyl) -1-oxa-8-azaspiro[4.5]decane is a PROTAC linker that can be used to synthesize ERD-1233.
Product Specifications
CAS Number
3026011-77-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
COC(OC)C(CO1)CC21CCNCC2
Molecular Formula
C11H21NO3
Molecular Weight
215.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Ranjan Kumar Acharyya, et al. Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer. J Med Chem. 2024 Nov 14;67 (21) :19010-19037.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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