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3- (Dimethoxymethyl) -1-oxa-8-azaspiro[4.5]decane

3- (Dimethoxymethyl) -1-oxa-8-azaspiro[4.5]decane is a PROTAC linker that can be used to synthesize ERD-1233.

Product Specifications

CAS Number

3026011-77-5

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

COC(OC)C(CO1)CC21CCNCC2

Molecular Formula

C11H21NO3

Molecular Weight

215.29

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Ranjan Kumar Acharyya, et al. Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer. J Med Chem. 2024 Nov 14;67 (21) :19010-19037.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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