Hydrouracil-4-fluorobenzoate
Hydrouracil-4-fluorobenzoate is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Hydrouracil-4-fluorobenzoate can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
CAS Number
2377643-38-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.84
Smiles
O=C(O)C1=CC=C(F)C(=C1)N2C(=O)NC(=O)CC2
Molecular Formula
C11H9FN2O4
Molecular Weight
252.20
Precautions
H302, H315, H319
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
Cereblon
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