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Hydrouracil-4-fluorobenzoate

Hydrouracil-4-fluorobenzoate is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Hydrouracil-4-fluorobenzoate can be linked to a target protein ligand via a linker to form a PROTAC.

Product Specifications

CAS Number

[2377643-38-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

98.84

Smiles

O=C(O)C1=CC=C(F)C(=C1)N2C(=O)NC(=O)CC2

Molecular Formula

C11H9FN2O4

Molecular Weight

252.20

Precautions

H302, H315, H319

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Isoform

Cereblon

Curated Selection

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