DBCO-PEG3-Maleimide

DBCO-PEG3-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324) . NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group[1].

Product Specifications

Product Name Alternative

DBCO-NHCO-PEG3-maleimide

UNSPSC

12352200

Hazard Statement

H302-H315-H319-H335

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Smiles

O=C(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)CCNC(CCOCCOCCOCCNC(CCN4C(C=CC4=O)=O)=O)=O

Molecular Formula

C34H38N4O8

Molecular Weight

630.69

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Hood ED, et al. Vascular Targeting of Radiolabeled Liposomes with Bio-Orthogonally Conjugated Ligands: Single Chain Fragments Provide Higher Specificity than Antibodies. Bioconjug Chem. 2018 Nov 21;29 (11) :3626-3637.