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L-Fucose

L-Fucose (6-Deoxy-L-galactopyranose) is an orally active dietary sugar. L-Fucose is one of the key metabolites involved in the interaction between humans and the intestinal microbiota. L-Fucose binds to proteins as a post-translational modification through the fucosylation process, thereby regulating the behavior and function of proteins. L-Fucose has shown the ability to inhibit tumor growth and increase the infiltration of immune cells within tumors. L-Fucose can be used in cancer and anti-tumor immune research[1].

Product Specifications

CAS Number

[87-96-7]

Product Name Alternative

6-Deoxy-L-galactopyranose

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Smiles

O[C@H]1[C@@H](O)[C@H](O)C(O)O[C@H]1C

Molecular Formula

C6H12O5

Molecular Weight

164.16

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Adhikari E, et al. L-fucose, a sugary regulator of antitumor immunity and immunotherapies. Mol Carcinog. 2022 May;61 (5) :439-453.|[2]Kim J, et al. L-Fucose is involved in human-gut microbiome interactions. Appl Microbiol Biotechnol. 2023 Jun;107 (12) :3869-3875.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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