ERK1/2 inhibitor 12
ERK1/2 inhibitor 12 (compound 76.3) is a ERK1/2 inhibitor which inhibits ERK-mediated phosphorylation of caspase-9 and the p90Rsk-1 kinase. ERK1/2 inhibitor 12 exhibits anti-cancer activity and can be utilized in cancer research[1].
Product Specifications
CAS Number
[350509-85-2]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
ERK
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C1S/C(C(N1CCN)=O)=C\C2=CC=C3OCOC3=C2
Molecular Formula
C13H12N2O4S
Molecular Weight
292.31
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Boston SR, et al. Characterization of ERK docking domain inhibitors that induce apoptosis by targeting Rsk-1 and caspase-9. BMC Cancer. 2011 Jan 10;11:7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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