5-Hydrazinyl thalidomide (hydrochloride)

5-Hydrazinyl thalidomide hydrochloride is a Thalidomide analogue featuring a hydrazine. PROTAC linkers are made to recruit E3 ligase for the ubiquitinylation of target proteins. The hydrazine may be used for further derivatization via reactions with various carbonyl groups.

Product Specifications

CAS Number

[2803460-96-8]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C1NC(C(CC1)N2C(C3=CC=C(NN)C=C3C2=O)=O)=O.Cl

Molecular Formula

C13H13ClN4O4

Molecular Weight

324.72

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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