5-Hydrazinyl thalidomide (hydrochloride)
5-Hydrazinyl thalidomide hydrochloride is a Thalidomide analogue featuring a hydrazine. PROTAC linkers are made to recruit E3 ligase for the ubiquitinylation of target proteins. The hydrazine may be used for further derivatization via reactions with various carbonyl groups.
Product Specifications
CAS Number
[2803460-96-8]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1NC(C(CC1)N2C(C3=CC=C(NN)C=C3C2=O)=O)=O.Cl
Molecular Formula
C13H13ClN4O4
Molecular Weight
324.72
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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