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Revefenacin impurity 4

Revefenacin impurity 4 (Compound 9b) is an intermediate of Revefenacin. Revefenacin impurity 4 can bind to human M3 muscarinic acetylcholine receptor inhibitors (Ki = 55 nM).

Product Specifications

CAS Number

1289178-27-3

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

MAChR

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Others

Smiles

O=C(NC1=C(C2=CC=CC=C2)C=CC=C1)OC3CCN(CC3)CC

Molecular Formula

C20H24N2O2

Molecular Weight

324.42

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Hughes AD, et al. Discovery of muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist (MABA) dual pharmacology molecules. Bioorg Med Chem Lett. 2011 Mar 1;21 (5) :1354-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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