(S, R, S) -AHPC 2-OH (hydrochloride)
(S, R, S) -AHPC 2-OH hydrochloride is an E3 ubiquitin ligase VHL ligand used to recruit the VHL protein. (S, R, S) -AHPC 2-OH hydrochloride can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
CAS Number
[2244684-41-9]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=C(O)C=C(C3=C(C)N=CS3)C=C2)=O)=O.Cl
Molecular Formula
C22H31ClN4O4S
Molecular Weight
483.02
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
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