(S, R, S) -AHPC-PEG2-NHS ester
(S, R, S) -AHPC-PEG2-NHS ester is a synthetic PROTAC linker that incorporatess an E3 ligase ligand with a PEG linker to empower PROTAC medicine chemistry. NHS ester is reactive with amine moiety. The hydrophilic PEG spacer increases its aqueous solubility.
Product Specifications
CAS Number
[2757045-58-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(CCC1=O)N1OC(CCOCCOCCC(NC(C(C)(C)C)C(N2[C@@H](C[C@H](C2)O)C(NCC3=CC=C(C4=C(C)N=CS4)C=C3)=O)=O)=O)=O
Molecular Formula
C34H45N5O10S
Molecular Weight
715.81
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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