Methosulide
Methosulide (Compound 1d) is a selective COX-2 inhibitor with an IC50 value of 2.31 μM. Methosulide can be used in the research of inflammatory diseases[1].
Product Specifications
CAS Number
51765-76-5
UNSPSC
12352005
Hazard Statement
H317
Target
COX
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
COC1=CC=C(C=C1)OC2=C(C=CC(=C2)[N+](=O)[O-])NS(=O)(=O)C
Molecular Formula
C14H14N2O6S
Molecular Weight
338.34
Precautions
P261-P272-P280-P302+P352-P362+P364-P501
References & Citations
[1]Yamamoto Y, et al. Isomeric methoxy analogs of nimesulide for development of brain cyclooxygense-2 (COX-2) -targeted imaging agents: Synthesis, in vitro COX-2-inhibitory potency, and cellular transport properties. Bioorg Med Chem. 2015 Nov 1;23 (21) :6807-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-1; COX-2
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