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MADAM

MADAM exhibits high affinity and selectivity for 5-HTT with a Ki value of 1.6 nM. MADAM has the potential to serve as a PET radiotracer for visualizing the serotonin transporter[1].

Product Specifications

CAS Number

411208-45-2

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Serotonin Transporter

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

NC1=CC(C)=CC=C1SC2=C(CN(C)C)C=CC=C2

Molecular Formula

C16H20N2S

Molecular Weight

272.41

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]J. Tarkiainen, et al. Carbon-11 labelling of madam in two different positions: A highly selective pet radioligand for the serotonin transporter. Journal of Labelled Compounds and Radiopharmaceuticals. Volume44, IssueS1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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