Paeonolsilate (sodium)
Paeonolsilate (sodium) can inhibit ox-LDL-induced macrophage foam cell formation and inflammation in atherosclerosis. Paeonolsilate (sodium) inhibits NF-κB activation and oxidative stress response induced by ox-LDL. Paeonolsilate (sodium) can be studied in anti-atherosclerosis research[1].
Product Specifications
CAS Number
827610-11-7
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NF-κB
Related Pathways
NF-κB
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
O=C(C)C1=C(O)C=C(OC)C(S(=O)(O[Na])=O)=C1
Molecular Formula
C9H9NaO6S
Molecular Weight
268.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Wenbo Fu, et al., (2016) . Sodium paeonolsilate inhibits ox-LDL induced macrophage foam cell formation andinflammation in atherosclerosis. Int J Clin Exp Med 2016;9 (2) :1051-1061. |[2]Kushiku, K., et al., (2001) . Upregulation of immunoreactive angiotensin II release and angiotensinogen mRNA expression by high-frequency preganglionic stimulation at the canine cardiac sympathetic ganglia. Circulation research, 88 (1), 110-116.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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