Polygodial pyridazine

Polygodial pyridazine (compound 7) is a polygodial analogue and a TRPV1 agonist with a GI50 of 72 μM against MCF-7. Polygodial pyridazine can be utilized in cancer research[1].

Product Specifications

CAS Number

[1810726-08-9]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

TRP Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Cancer

Smiles

C[C@@]12[C@](CCC3=CN=NC=C32)([H])C(C)(CCC1)C

Molecular Formula

C15H22N2

Molecular Weight

230.35

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Dasari R, et al. Synthetic and Biological Studies of Sesquiterpene Polygodial: Activity of 9-Epipolygodial against Drug-Resistant Cancer Cells. ChemMedChem. 2015 Dec;10 (12) :2014-26.