PDE4-IN-25
PDE4-IN-25 (compound 12) is a potent inhibitor of PDE4, with the IC50 of 0.1 μM. PDE4-IN-25 plays an important role in inflammatory diseases research[1].
Product Specifications
CAS Number
346440-86-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=C(C)N(C2=CC([N+]([O-])=O)=CC=C2)N=C1C)OCC
Molecular Formula
C14H15N3O4
Molecular Weight
289.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Icos Corp. Preparation of pyrazoles as cAMP-specific phosphodiesterase inhibitors for pharmaceutical use as anti-inflammatory agents. World Intellectual Property Organization, WO2001046172 A1 2001-06-28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4
Available Sizes
Frequently Asked Questions
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