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PDE4-IN-25

PDE4-IN-25 (compound 12) is a potent inhibitor of PDE4, with the IC50 of 0.1 μM. PDE4-IN-25 plays an important role in inflammatory diseases research[1].

Product Specifications

CAS Number

346440-86-6

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Phosphodiesterase (PDE)

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Smiles

O=C(C1=C(C)N(C2=CC([N+]([O-])=O)=CC=C2)N=C1C)OCC

Molecular Formula

C14H15N3O4

Molecular Weight

289.29

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Icos Corp. Preparation of pyrazoles as cAMP-specific phosphodiesterase inhibitors for pharmaceutical use as anti-inflammatory agents. World Intellectual Property Organization, WO2001046172 A1 2001-06-28.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PDE4

Available Sizes

Frequently Asked Questions

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