Avermectin A1a

Avermectin A1a is a potent and broad-spectrum antiparasitic agent. Avermectin A1a targets nematodes and arthropods by binding to their glutamate-gated chloride channels to block nerve signal transmission and induce paralysis. Avermectin A1a can be used for the study of parasitic infection[1].

Product Specifications

CAS Number

[65195-51-9]

UNSPSC

12352005

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O[C@@H]1[C@H](C[C@@]([H])(O[C@H]1C)O[C@H]2[C@@H](O[C@]([H])(C[C@@H]2OC)O[C@H](/C(C)=C/C[C@]3(O[C@]4(CC(C3)OC5=O)C=C[C@@H]([C@]([H])(O4)[C@@H](C)CC)C)[H])[C@H](/C=C/C=C6[C@@]7([C@]([H])(OC/6)[C@@H](C(C)=C[C@]75[H])OC)O)C)C)OC

Molecular Formula

C49H74O14

Molecular Weight

887.10

References & Citations

[1]Jenke-Kodama H, et al. Natural biocombinatorics in the polyketide synthase genes of the actinobacterium Streptomyces avermitilis. PLoS Comput Biol. 2006 Oct 6;2 (10) :e132.