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Suptopin-2

Sutopin-2 is a topoisomerase II inhibitor. Suptopin-2 affects cell cycle progression and stability of microtubules. Sutopin-2 induces cell cycle arrest by regulating the nucleocytoplasmic transport of cyclin B1[1].

Product Specifications

CAS Number

331852-66-5

UNSPSC

12352005

Target

Topoisomerase

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C1OC(C)=CC(O)=C1C(/C=C/C2=CC(OC)=C(O)C(OC)=C2)=O

Molecular Formula

C17H16O7

Molecular Weight

332.30

References & Citations

[1]Haggarty SJ, et al. Small molecule modulation of the human chromatid decatenation checkpoint. Chem Biol. 2003;10 (12) :1267-1279.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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