Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Propanoic acid-13C3

Propanoic acid-13C3 is the 13C-labeled Propanoic acid. Propanoic acid is an orally active short-chain fatty acid. Propanoic acid can be produced by intestinal bacteria from the metabolism of dietary fiber. Propanoic acid increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Propanoic acid also induces Apoptosis and Autophagy. Propanoic acid reduces HSV-1-induced keratitis. Propanoic acid has anticancer effects against glioblastoma. Propanoic acid exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Propanoic acid can be used in the research of spinal cord injury and Alzheimer's disease[1][2][3][4][5][6][7].

Product Specifications

CAS Number

153474-35-2

UNSPSC

12352211

Hazard Statement

H226-H314

Target

Apoptosis; Autophagy; Bacterial; COX; Endogenous Metabolite; HSV; Isotope-Labeled Compounds; NF-κB; NO Synthase; PPAR

Related Pathways

Anti-infection; Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Inflammation/Immunology; Neurological Disease

Smiles

O[13C]([13CH2][13CH3])=O

Molecular Formula

13C3H6O2

Molecular Weight

77.06

Precautions

P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P370+P378-P403+P235-P405-P501

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Filippone A, et al. Sodium Propionate Contributes to Tumor Cell Growth Inhibition through PPAR-γ Signaling. Cancers (Basel) . 2022 Dec 29;15 (1) :217. |[3]Filippone A, et al. The anti-inflammatory and antioxidant effects of sodium propionate. International journal of molecular sciences, 2020, 21 (8) : 3026.|[4]Filippone A, et al. Protective effect of sodium propionate in Aβ1-42-induced neurotoxicity and spinal cord trauma. Neuropharmacology. 2020 Apr;166:107977. |[5]Park HS, et al. Sodium propionate exerts anticancer effect in mice bearing breast cancer cell xenograft by regulating JAK2/STAT3/ROS/p38 MAPK signaling. Acta Pharmacol Sin. 2021 Aug;42 (8) :1311-1323. |[6]Sumbria D, et al. Supplementing the Diet with Sodium Propionate Suppresses the Severity of Viral Immuno-inflammatory Lesions. J Virol. 2021 Jan 28;95 (4) :e02056-20. |[7]Lang W, et al. Sodium propionate improves cognitive and memory function in mouse models of Alzheimer's disease. Neurosci Lett. 2022 Nov 20;791:136887.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

S100B (Astrocyte and Melanoma Marker) (S100B/1706R), 0.2mg/mL
BNUB1706-500 1x 500 µL

S100B (Astrocyte and Melanoma Marker) (S100B/1706R), 0.2mg/mL

Sign In for Pricing
View Details
Recombinant Cdc27 Monoclonal Antibody
AN301730L-01 50 µL

Recombinant Cdc27 Monoclonal Antibody

Sign In for Pricing
View Details
Recombinant Cdc27 Monoclonal Antibody
AN301730L-02 100 µL

Recombinant Cdc27 Monoclonal Antibody

Sign In for Pricing
View Details
CD34 Class I Mouse Monoclonal Antibody [Clone ID: B-C34]
AM31235PU-N 2 mL (200 Tests)

CD34 Class I Mouse Monoclonal Antibody [Clone ID: B-C34]

Sign In for Pricing
View Details
EPHB1/2/3 Antibody
8C15651-AAT 50 µg

EPHB1/2/3 Antibody

Sign In for Pricing
View Details
PP1C gamma (PPP1CC) (N-term) Rabbit Polyclonal Antibody
AP15243PU-N 400 µL

PP1C gamma (PPP1CC) (N-term) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details