MeIQx-13C
MeIQx-13C (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2-13C) is the 13C-labeled MeIQx. MeIQx, a dietary aromatic amine, is mutagenic compound could be isolated from present in fried beef and beef extracts. MeIQx binds covalently to hemoglobin. MeIQx induces liver tumors[1][2].
Product Specifications
CAS Number
209977-58-2
Product Name Alternative
2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2-13C
UNSPSC
12352005
Target
Cytochrome P450; Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
CC1=NC2=C(N=C1)C=CC3=C2N=[13C](N3C)N
Molecular Formula
C10 13CH11N5
Molecular Weight
214.23
References & Citations
[1]Lynch AM, et, al. The measurement of MeIQx adducts with mouse haemoglobin in vitro and in vivo: implications for human dosimetry. Carcinogenesis. 1991 Jun;12 (6) :1067-72.|[2]Ohgaki H, et, al. Carcinogenicity in mice of a mutagenic compound, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) from cooked foods. 1987 May;8 (5) :665-8.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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