MeIQx-13C

MeIQx-13C (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2-13C) is the 13C-labeled MeIQx (HY-W355129) . MeIQx, a dietary aromatic amine, is mutagenic compound could be isolated from present in fried beef and beef extracts. MeIQx binds covalently to hemoglobin. MeIQx induces liver tumors[1][2].

Product Specifications

CAS Number

[209977-58-2]

Product Name Alternative

2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2-13C

UNSPSC

12352005

Target

Cytochrome P450; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

CC1=NC2=C(N=C1)C=CC3=C2N=[13C](N3C)N

Molecular Formula

C10 13CH11N5

Molecular Weight

214.23

References & Citations

[1]Lynch AM, et, al. The measurement of MeIQx adducts with mouse haemoglobin in vitro and in vivo: implications for human dosimetry. Carcinogenesis. 1991 Jun;12 (6) :1067-72.|[2]Ohgaki H, et, al. Carcinogenicity in mice of a mutagenic compound, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) from cooked foods. 1987 May;8 (5) :665-8.